The Uterine Sound Podcast

Episode 7: Obstetric Anal Sphincter Injuries (OASIS)

Join hosts Carla, Mel and Anne in another action-packed episode of the Uterine Sound Podcast as we cover the gripping topic of OASIS. 

From risk factors and classification of perineal tears, to the complications that may occur if these tears are undetected, this episode has it all. Understand the importance of identifying and repairing sphincter injuries correctly, and learn about evidence based post-operative management. 

With heart-pounding intensity, they dissect the latest evidence on perineal massage, pelvic floor exercises, and the use of episiotomies. Prepare for a gripping discussion on intrapartum prevention techniques, including warm compresses, birthing positions, and the controversial hands-on approach. And don't miss out on the riveting WHA Collaborative Care Bundle, designed to reduce OASIS rates by 20%. It's a rollercoaster ride of knowledge that will leave you eager for more.

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Episode 6: Evidence with Anne - PPROM Trials

Get ready for the debut episode of "Evidence with Anne" on the thrilling Uterine Sound podcast! Hosted by the dynamic trio, Carla, Mel, and Anne, this episode dives deep into the pulse-pounding world of Preterm Prelabour Rupture of Membranes (PPROM) and its landmark trials.

Hold your breath as they unravel the mysteries of the ORACLE I trial, where antibiotics take centre stage in the epic battle for neonatal outcomes. Discover the power of erythromycin, the hero reducing morbidity and mortality, while the sinister co-amoxiclav raises the spectre of NEC.

But the action doesn't stop there! The ORACLE II trial enters the fray, adding a twist to the tale with its unexpected findings. Brace yourself as the hosts navigate through functional impairments and cerebral palsy, shedding light on the long-term effects of these treatments.

In a heart-pounding showdown, the PPROMT trial takes the spotlight, where immediate delivery faces off against expectant management. Witness the fierce clash of neonatal sepsis rates, respiratory distress, and NICU battles, while APH and caesarean sections add to the adrenaline rush.

And just when you think the excitement is over, the PPROMEXIL trial steps into the ring with its 10-year follow-up! Can it provide the answers to the ultimate question: What are the long-term outcomes for these little warriors?

Listen now on Spotify & Podbean.

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Check out our website: www.theuterinesound.com

Episode 5: Preterm Birth (Part 3)

Welcome to part three of our exciting mini-series on Preterm Birth!

In this thrilling episode of the Uterine Sound podcast, hosts Carla, Mel, and Anne take their listeners on a captivating journey through the world of preterm birth prevention. Join them as they delve into the intricacies of this complex topic, exploring risk factors and evidence-based interventions that can help reduce the chances of preterm birth.

From modifiable risk factors like smoking and BMI to the fascinating realm of cervical length screening, the hosts share valuable insights and practical tips for predicting and preventing preterm birth. Discover how a simple ultrasound measurement can hold the key to identifying those at higher risk and how progesterone, the "superstar" hormone, can make a significant impact on reducing preterm birth rates.

But the excitement doesn't stop there! The hosts also unravel the mystery surrounding cerclage, the "stitch" that holds the cervix shut, and when it becomes a powerful tool in the fight against preterm birth.

Tune in to this captivating episode filled with evidence-based knowledge, engaging anecdotes, and intriguing revelations that every O&G enthusiast must hear. Don't miss out on the valuable pearls of wisdom that could make a life-changing difference in the world of preterm birth prevention.

Listen now on Spotify & Podbean! 

www.theuterinesound.com

 

 

Episode 4: Preterm Birth (Part 2)

In part two of our miniseries on Preterm Birth, Mel, Carla and Anne dive further into the critical topic of preterm birth and explore its diagnosis and management.

They cover the history, examination, and tests used in diagnosing preterm labour. The hosts then go through the evidence that has shaped current management, including corticosteroids, tocolysis and magnesium sulphate. This is all followed by a look at the up-and-coming research, as well!

Keep an eye out for some Instagram posts with stats on the different diagnostic tests...

Enjoy - let us know what you learnt and don't be shy if you've found a mistake or have any questions.

Listen on Spotify & Podbean!

And get in touch with us on Instagram (@theuterinesound) or via email (theuterinesound@gmail.com)

Episode 3: Preterm Birth (Part 1)

Get ready for another exciting episode of the Uterine Sound podcast! Join hosts Anne, Carla, and Mel as they explore the captivating world of preterm labour. Discover the shocking impact of preterm birth, with millions of babies affected each year and significant long-term consequences. Unravel the four pathways leading to preterm labour. Delve into risk factors, including demographics, lifestyle choices, previous complications, genetics, and even the influence of a baby's gender.

Learn about cervical insufficiency, cervical surgery, and the connection between infections and preterm birth. Explore the world of risk scoring systems, biomarkers, and screening tests for predicting preterm birth. Be aware of their limitations and the need for further validation.

Get ready for an exhilarating journey with the Uterine Sound podcast – where knowledge meets excitement and revolutionizes your understanding of preterm birth. Let the adventure begin!

Let us know what you think and don't forget to follow us on socials.

www.theuterinesound.com

@theuterinesound

theuterinesound@gmail.com

Episode 2: Group B Strep

Episode 2: Group B Strep

In Episode 2 of the Uterine Sound Podcast, hosts Anne, Carla and Mel provide an informative discussion on Group B Strep (or The Lancefield Group B beta haemolytic streptococcus agalactiae, as you'll soon be reminded)!

Uncover the essentials of GBS, it's impact during pregnancy, and the measures taken to safeguard both mothers and newborns. From explaining the nature of GBS to discussing testing methods and risk factors, the hosts deliver a comprehensive overview. Discover the benefits and considerations of universal screening versus a risk-based approach for GBS detection. Explore the significance of Intrapartum Antibiotic Prophylaxis in reducing GBS-related risks.

The hosts also touch upon ongoing research in GBS vaccination during pregnancy and advancements in testing methods. With their engaging style, The Uterine Sound Podcast ensures that healthcare professionals and students stay up to date on the latest insights for protecting mothers and newborns from the risks associated with Group B Strep.

Don't miss this exciting episode! Tune in to The Uterine Sound Podcast for a concise and informative exploration of GBS in Obstetrics & Gynaecology. Visit our website for references, and follow us on Instagram @theuterinesound for captivating visual summaries. 

 

Episode 1: PPROM

Join hosts Anne, Mel, and Carla on an exciting episode of The Uterine Sound podcast as they delve into the mysterious world of PPROM (Preterm Pre-labour rupture of membranes). Uncover the incidence, risk factors, diagnosis, and management of this condition that affects 3% of pregnancies and is associated with 30-40% of preterm births. From exploring the complex interplay between extracellular membrane proteins and matrix metalloproteases to discussing the important diagnostic tests and their accuracy, this episode will keep you on the edge of your seat. We'll also discuss the important trials, experimental therapies and special situations like women with cerclage, meconium liquor, HSV/HIV. 

 

Let us know what you think and don't forget to follow us on socials.

www.theuterinesound.com

@theuterinesound

theuterinesound@gmail.com

 

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Reference List:

Up-to-date: PPROM: Management and Outcome 

Up-to-date: PPROM: Clinical manifestations and diagnosis 

Up-to-date: Prelabour rupture of membranes before and at the limit of viability 

RCOG Green Top Guideline 73: Care of women presenting with suspected preterm prelabour rupture of membranes from 24+0 weeks of gestation “Thomson AJ, on behalf of the Royal College of Obstetricians and Gynaecologists. Care of Women Presenting with Suspected Preterm Prelabour Rupture of Membranes from 24+0 Weeks of Gestation. BJOG 2019;126:e152–166” 

RCOG Green Top Guideline 36: Prevention of Early Onset Group B Streptococcal Disease 

ACOG Practice Bulletin 217: Prelabour Rupture of Membranes Jan 2018  

SOGC No 233: Antibiotic therapy in PPROM 

Ramsauer B, Vidaeff AC, Hösli I, Park JS, Strauss A, Khodjaeva Z, de la Cruz ÁA, Martínez-Astorquiza T, Horovitz J, Coatleven F, Helmer H. The diagnosis of rupture of fetal membranes (ROM): a meta-analysis. J Perinat Med. 2013 May;41(3):233-40. doi: 10.1515/jpm-2012-0247. PMID: 23314505. 

Kenyon SL, Taylor DJ, Tarnow-Mordi W; ORACLE Collaborative Group. Broad-spectrum antibiotics for preterm, prelabour rupture of fetal membranes: the ORACLE I randomised trial. ORACLE Collaborative Group. Lancet. 2001 Mar 31;357(9261):979-88. doi: 10.1016/s0140-6736(00)04233-1. Erratum in: Lancet 2001 Jul 14;358(9276):156. PMID: 11293640. 

Kenyon SL, Taylor DJ, Tarnow-Mordi W; ORACLE Collaborative Group. Broad-spectrum antibiotics for spontaneous preterm labour: the ORACLE II randomised trial. ORACLE Collaborative Group. Lancet. 2001 Mar 31;357(9261):989-94. doi: 10.1016/s0140-6736(00)04234-3. PMID: 11293641. 

Morris JM, Roberts CL, Bowen JR, Patterson JA, Bond DM, Algert CS, Thornton JG, Crowther CA; PPROMT Collaboration. Immediate delivery compared with expectant management after preterm pre-labour rupture of the membranes close to term (PPROMT trial): a randomised controlled trial. Lancet. 2016 Jan 30;387(10017):444-52. doi: 10.1016/S0140-6736(15)00724-2. Epub 2015 Nov 10. PMID: 26564381. 

van der Ham DP, Vijgen SM, Nijhuis JG, van Beek JJ, Opmeer BC, Mulder AL, Moonen R, Groenewout M, van Pampus MG, Mantel GD, Bloemenkamp KW, van Wijngaarden WJ, Sikkema M, Haak MC, Pernet PJ, Porath M, Molkenboer JF, Kuppens S, Kwee A, Kars ME, Woiski M, Weinans MJ, Wildschut HI, Akerboom BM, Mol BW, Willekes C; PPROMEXIL trial group. Induction of labor versus expectant management in women with preterm prelabor rupture of membranes between 34 and 37 weeks: a randomized controlled trial. PLoS Med. 2012;9(4):e1001208. doi: 10.1371/journal.pmed.1001208. Epub 2012 Apr 24. PMID: 22545024; PMCID: PMC3335867.  

Tajik P, van der Ham DP, Zafarmand MH, Hof MH, Morris J, Franssen MT, de Groot CJ, Duvekot JJ, Oudijk MA, Willekes C, Bloemenkamp KW, Porath M, Woiski M, Akerboom BM, Sikkema JM, Nij Bijvank B, Mulder AL, Bossuyt PM, Mol BW. Using vaginal Group B Streptococcus colonisation in women with preterm premature rupture of membranes to guide the decision for immediate delivery: a secondary analysis of the PPROMEXIL trials. BJOG. 2014 Sep;121(10):1263-72; discussion 1273. doi: 10.1111/1471-0528.12889. Epub 2014 May 27. PMID: 24862166. 

Bond DM, Middleton P, Levett KM, van der Ham DP, Crowther CA, Buchanan SL, Morris J. Planned early birth versus expectant management for women with preterm prelabour rupture of membranes prior to 37 weeks' gestation for improving pregnancy outcome. Cochrane Database Syst Rev. 2017 Mar 3;3(3):CD004735. doi: 10.1002/14651858.CD004735.pub4. PMID: 28257562; PMCID: PMC6464692. 

Mercer BM, Miodovnik M, Thurnau GR, Goldenberg RL, Das AF, Ramsey RD, Rabello YA, Meis PJ, Moawad AH, Iams JD, Van Dorsten JP, Paul RH, Bottoms SF, Merenstein G, Thom EA, Roberts JM, McNellis D. Antibiotic therapy for reduction of infant morbidity after preterm premature rupture of the membranes. A randomized controlled trial. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. JAMA. 1997 Sep 24;278(12):989-95. PMID: 9307346.  

Introduction

The Uterine Sound Podcast is a medical education resource for Obstetrics and Gynaecology trainees or anyone interested in learning about O&G. Hosted by Anne, Mel, and Carla, the podcast aims to provide concise and comprehensive information on Obstetrics & Gynaecology. The hosts discuss their motivation for starting the podcast, the scarcity of O&G podcasts, and the need for a resource that gets straight to the point. They introduce themselves briefly, highlighting their backgrounds and interests. The hosts assure listeners that the podcast will cover all necessary topics and encourage engagement through Instagram and email.